Mesna is a drug used to prevent bleeding in the bladder (hemorrhagic cystitis) and kidney during chemotherapy with Ifosfamide (Ifex) and Cyclophosphamide. Mesna is not a chemotherapy drug. While you are given the treatment, your urine is closely monitored and tested for any signs of blood. If blood is present in your urine, you will be given extra Mesna.
Dosage :Mesna 100mg/1ml, Mesna 200mg/2ml, Mesna 400mg/4ml, Mesna 600mg/6ml
How it is Administered
Directly into the vein using a fine tube, cannula. It is given in the drip form mixed with sterile, salty water (saline) or in combination with your chemotherapy
It can also be infused with central pipe line inserted under the skin and into a vein near the collarbone or passed through a vein in their arm (a PICC line)
Since Mesna is given along with the chemotherapy drugs it is difficult to distinguish its side effects. There has been very few of the side effects that have been practically experienced or noticed. If you experience any of the side effect mentioned below, immediately discuss it with your doctor.
Diarrhea or soft stools that may cause discomfort or colic (wind)
Limb and joint pain
Irritability and mood changes